Charlie Hodgson and Andrew Sheridan have been ruled out for the rest of the season.
Sale have confirmed that their England international duo Charlie Hodgson and Andrew Sheridan will miss the remainder of the season.The pair suffered serious injuries during England's Test victory over South Africa at Twickenham on Saturday.
The news is a serious blow to Sale's faltering bid to retain their Premiership title as well as to national coach Andy Robinson as he gears up for the Six Nations and the World Cup next year.
Fly-half Hodgson will undergo surgery next week after rupturing his cruciate ligament, while Sheridan is also due to go under the knife after fracturing his ankle and sustaining ligament damage.
Director of Rugby Philippe Saint Andre said: "This is a terrible blow for the players, for England and for Sale Sharks.
"Our thoughts are with the players at this moment, but we know that they will receive the very best treatment available to ensure that they return, for club and country, as soon as is possible.
"Of course their loss is a blow to our aspirations to retain our title, and also to our chances in the EDF and Heineken Cups.
"However, I have a strong squad here at Sale, and opportunities will now open up for some of our younger players to make a name for themselves. We will not be making excuses - we must instead be inspired by adversity."
England beat South Africa to snap a record-breaking seven-match losing sequence, but the injuries have left a sour taste for head coach Robinson.
"Everyone feels for Charlie and Andrew and we wish them all the best for their recovery," he said.
"They are key members of the squad and they have contributed massively this autumn. Their absence will be a real blow to England and Sale Sharks."
