Newcastle, Exeter, London Irish, Cardiff and Connacht recorded bonus-point wins in the Challenge Cup.
Connacht have confirmed head coach Pat Lam has signed a three-year extension to his contract.
Exeter produced a powerful second-half display to win at Connacht and reach the European Challenge Cup quarter-finals.
Connacht centre Bundee Aki has been ruled out for up to 10 weeks as he requires ankle surgery.
Watch all the highlights of this weekend's Guinness PRO12 action.
Edinburgh ended Connacht’s unbeaten home record this season with a 16-13 win at the Sportsground on Friday night.
Connacht head coach Pat Lam has expressed his delight at extending Quinn Roux's loan deal until the end of the season.
Connacht produced a superb comeback to secure a 24-16 victory over inter-provincial rivals Munster in Galway.
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