Cardiff Blues host Munster in Sky Sports live fixture, Ulster take on the Dragons while Scarlets entertain Zebre.
Scarlets claimed a first win of their European Champions Cup campaign with a gutsy 15-3 triumph over Leicester Tigers.
Wayne Pivac paid tribute to the Scarlets after they claimed the scalp of Leicester in the European Champions Cup.
After a valiant effort against defending champions Toulon, Scarlets welcome Leicester Tigers to the Parc y Scarlets.
Jonny Wilkinson, Will Greenwood and Nick Easter analyse all the action from the opening weekend.
Toulon made a winning start to their Champions Cup campaign as they recorded a 28-18 victory over the Scarlets.
Wales international Leigh Halfpenny was pleased to put a frustrating period behind him on his home debut for Toulon.
Reigning kings of Europe Toulon kick-off their Champions Cup campaign against Scarlets in a real David v Goliath clash.
The Manchester derby live only on Sky Sports
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