Saturday's Aviva Premiership bill sees Northampton host Bath, London Irish visit Leicester and Saracens clash with Sale.
A last-minute try by Billy Vunipola saw Saracens beat London Irish 36-32 in the Aviva Premiership.
Brian Smith was proud of London Irish's performance after their last-gasp defeat to Saracens in the Aviva Premiership.
England's 12 Premiership clubs will share in a compensation pot of around £13m after settling a dispute with the RFU.
Saturday’s Premiership action sees two London derbies, a battle of fly-halves, while London Welsh and Sale lock horns.
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