Harlequins withstood a second-half comeback from Sale Sharks to win 25-23 at the AJ Bell Stadium.
Joe Marler will miss the remainder of the season with a shoulder injury but he should be fit for the World Cup.
Sale Sharks face Harlequins at the AJ Bell Stadium on Saturday looking to keep their faint top six hopes alive.
Harlequins have signed Samoa international centre Winston Stanley in a deal which will run from next season.
Mike Brown may not play for Harlequins again this season due to side effects from a concussion suffered two months ago.
Harlequins scored two late tries to snatch a 29-26 victory over Gloucester at The Stoop.
Harlequins make five changes for Saturday’s Aviva Premiership visit of Gloucester to The Stoop.
Fly-half Tim Swiel will return to Harlequins next season on a full-time contract.
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