England Saxons have named Jonny May and Matt Mullan in their starting line-up for Friday night's televised clash with Scotland A at Kingston Park.
Gloucester flyer May takes over from Christian Wade on the right wing and Worcester Warriors' prop Mullan replaces Nick Wood at loose head.
Head coach Jon Callard has kept changes to a minimum to build on the momentum established with last week's 14-10 win against the O2 Ireland Wolfhounds in Galway.
Meanwhile, Scotland chief Shade Munro is hoping to guide his side to a home and away double over England Saxons following their 35-0 triumph at Netherdale last time around.
Ten of the squad that secured the emphatic win last year went on to earn full international honours, with six of the 22-man squad returning to face the Saxons once more; centre Alex Grove, prop Jon Welsh, lock Tom Ryder and back-row trio Stuart McInally, Richie Vernon and captain Ryan Wilson.
Bath's Tom Heathcote, who earned his first and only cap to date in the 2012 EMC Tests, starts at stand-off alongside 21-year-old scrum-half, Sean Kennedy, one of the eight uncapped players in the starting-line-up.
Fellow uncapped Warrior Alex Dunbar steps into the inside-centre slot to partner Grove in midfield, while Nikki Walker will add to his 24 caps after injury.
England Saxons: 15 Elliot Daly (Wasps), 14 Jonny May (Gloucester), 13 Joel Tomkins (Saracens), 12 Jordan Turner-Hall (Harlequins), 11 Tom Biggs (Bath), 10 George Ford (Leicester), 9 Richard Wigglesworth (Saracens); 1 Matt Mullan (Worcester), 2 Joe Gray (Harlequins), 3 Paul Doran-Jones (Northampton), 4 Graham Kitchener (Leicester), 5 George Robson (Harlequins), 6 George Kruis (Saracens), 7 Will Fraser (Saracens), 8 Jordan Crane (Leicester, captain).
Replacements: 16 Rob Buchanan (Harlequins), 17 Nick Wood (Gloucester), 18 Kieran Brookes (Leicester), 19 Ed Slater (Leicester), 20 Jamie Gibson (London Irish), 21 Joe Simpson (Wasps), 22 George Lowe (Harlequins), 23 Kyle Eastmond (Bath).
Scotland A: 15 Greig Tonks (Edinburgh), 14 Duncan Taylor (Saracens), 13 Alex Grove (Worcester), 12 Alex Dunbar (Glasgow), 11 Nikki Walker (Worcester), 10 Tom Heathcote (Bath), 9 Sean Kennedy (Glasgow), 1 Alasdair Dickinson (Sale), 2 Steven Lawrie (Edinburgh), 3 Jon Welsh (Glasgow), 4 Tom Ryder (Glasgow), 5 Tim Swinson (Glasgow), 6 Stuart McInally (Edinburgh), 7 Richie Vernon (Sale), 8 Ryan Wilson (Glasgow, capt).
Replacements: 16 Alun Walker (Edinburgh), 17 Grant Shiells (Newcastle), 18 Gordon Reid (Glasgow), 19 Robert McAlpine (Edinburgh), 20 James Eddie (Glasgow), 21 Jamie Stevenson (London Scottish), 22 Ben Cairns (Edinburgh), 23 Dougie Fife (Edinburgh).
What they said...
England Saxons head coach Jon Callard
"Jonny May and Matt Mullan are both talented players who've trained hard to earn the chance to show what they can do against Scotland.
"If you don't get it right at international level, sides like this Scotland one will punish you heavily and that's what happened last year. We've all learned from that and we're determined to get it absolutely right this time round."
Scotland head coach Shade Munro
"This is the first senior representative match of 2013 for a Scottish side and, as an opener for the RBS Six Nations Championship, we have the opportunity to put a marker down and show what Scottish rugby is about, while those selected have an excellent chance to show why they deserve to feature in the remainder of the RBS Six Nations campaign."