Plymouth Argyle secured a first victory of the League Two season as Morecambe held on to top spot despite losing at home.
Shrewsbury Town climbed in to second after Rotherham United were hammered by Southend United and Crawley Town overcame Aldershot Town.
AFC Wimbledon picked up three points at Bradford City, the local derby between Crewe Alexandra and Port Vale ended all square, while Burton Albion had two players sent off in defeat at Gillingham.
Warren Feeney and Robbie Williams scored the goals to give new manager Carl Fletcher a perfect start to his reign as Plymouth won for the first time this term by beating Macclesfield Town 2-0 at Home Park.
Morecambe are hanging on to pole position on goal difference after suffering a 3-2 defeat at home by Bristol Rovers in a topsy-turvy game at the Globe Arena.
James Collins netted a goal in each half as Shrewsbury joined Morecambe at the summit thanks to a 2-0 home success over Torquay United.
Southend are now in the automatic promotion positions after beating previously second-placed Rotherham 4-0 away from home, with Michael Timlin scoring a brace.
Michael Doughty notched the only goal of the game on 64 minutes as Crawley enjoyed a 1-0 success at Aldershot.
Tom Pope returned to haunt his former club Crewe as the striker scored the equaliser in Port Vale's 1-1 draw at Gresty Road.
Christian Jolley grabbed a second-half winner as AFC Wimbledon came from behind to claim a 2-1 win at struggling Bradford.
Burton finished the game with nine men at Priestfield as Danny Kedwell plundered a brace in Gillingham's 3-1 triumph.
Peter Murphy netted a second-half equaliser as Accrington Stanley drew 1-1 at Oxford United, while Hereford United drew 0-0 at Cheltenham Town.
Matt Ritchie scored a goal in each half as Swindon Town enjoyed an emphatic 4-0 victory over Barnet at the County Ground.
Northampton Town collected a first win at Sixfields this term as goals from Arron Davies and Adebayo Akinfenwa secured a 2-1 success over Dagenham & Redbridge.