The former Wimbledon striker volleyed home on 42 minutes from a David Bell Jnr corner before the provider turned to goalscorer when he scored with 20 minutes left on the clock before Holdsworth scored his second two minutes later.
The win takes Brian Talbot's men another step closer to snatching the title ahead of Hartlepool United as they extend their lead to four points over Pool.
Hartlepool's poor form of late continued against Rochdale at the Victoria Ground as they could only manage a 2-2 draw.
The already promoted outfit fell behind when defender Simon Grand popped up with a goal on 23 minutes for the visitors before Tommy Widdrington scored on 42 minutes after Richie Humphreys' initial effort was blocked by Matthew Gilks.
Lee McEvilly then came up with a spectacular goal for the away side as he rifled the ball into the top corner from outside the penalty area on 45 minutes but Widdrington again equalised less than ten minutes after the interval.
Wrexham moved another step closer to the third automatic promotion spot thanks to a 6-1 thumping of lowly Carlisle.
The Dragons goal machine Andy Morrell continued his fantastic season in front of goal when he converted from the penalty spot after 22 minutes.
Morrell then got his and his side's second ten minutes later when he slotted home a Darren Ferguson corner at the near post on 34 minutes to take his personal tally to 33 goals for the season before Brian Carey made it three five minutes later before notching his second on 54 minutes.
Brian Wake scored a consolation for Carlisle on 68 minutes before Morrell completed his hat-trick with five minutes remaining and Carlos Edwards completed the rout three minutes before the end but Denis Smith's side will have to wait though before joining Hartlepool and Rushden in Divison Two as Bournemouth were also victorious on Monday afternoon.
Bournemouth kept up the heat on Wrexham in third place with a 2-1 win over Shrewsbury Town.
Sam Aiston, who scored in the heart-breaking 3-2 defeat to Macclesfield Town last week drilled home from the edge of the box to give The Shrews the lead after five minutes.
Bournemouth hauled themselves level on 21 minutes when Scott McDonald, the young Australian on-loan from Premiership side Southampton, scored before Wade Elliott compounded Town's misery by walking the ball into the net on the stroke of half-time.
It was Elliott's first goal in 28 games as the South Coast condemned Town to the foot of the table.
Bristol Rovers did their chances of survival no harm as they scored an important victory over play-off hopefuls Oxford United at The Kassam stadium.
Veteran forward Andy Rammell netted from close range to put six points between themselves and Shrewsbury Town at the bottom of the table.
Torquay continued their hunt for an end of season play-off place and took the lead thanks to a Jo Kuffour strike on 26 minutes.
Gary Alexander found an equaliser for the Brisbane Road side five minutes before the interval though but Orient's resistance looked to have collapsed when David Graham came up with a goal on 65 minutes.
Gary Fletcher came to The O's rescue though as he scored the equaliser on 73 minutes.
Darlington secured a 2-0 victory over fellow mid-table side Hull City at the Feethams Ground.
Tom Newey managed to get on the end of a Barry Conlan cross before Conlan himself netted to ensure maximums points for the North East side.
Boston United did their chances of survival more good with a 1-0 win over Essex side Southend United at York Street.
Mark Angel got the all important goal with a penalty five minutes from time.
Exeter dragged themselves off the foot of the table as they showed they will not be giving up their league status without a fight with a 1-0 win over fellow strugglers Swansea City.
The win keeps them in one of the two relegation places but Sean Devine's goal could be one of the most important in the club's history if they are to stay up this season.
Bury managed to pick up a point to aid their play-off hopes with a 0-0 draw against Scunthorpe United while York City and Kidderminster Harriers also saw out a goalless affair.
For full Nationwide Division Three match summaries click below
Boston Utd 1-0 Southend
Bournemouth 2-1 Shrewsbury
Bury 0-0 Scunthorpe
Darlington 2-0 Hull
Hartlepool 2-2 Rochdale
Oxford Utd 0-1 Bristol Rovers
Rushden & D'monds 3-0 Macclesfield
Swansea 0-1 Exeter
Torquay 2-2 Leyton Orient
Wrexham 6-1 Carlisle
York 0-0 Kidderminster
Click here for updated Division Three table
