Birmingham have moved top of The Championship thanks to a 2-0 win over QPR, while Cardiff and Wolves both dropped points.
Steve Bruce's side took the lead at Loftus Road thanks to Bruno N'Gotty's opener after 23 minutes, although they finished the game a man light.
They did it the hard way when Nicklas Bendtner collected a second yellow card, however Cameron Jerome made sure of the points late on with a fine lobbed finish.
Cardiff City missed the chance to fend off Birmingham at the summit of the table after throwing away a three-goal lead at Plymouth.
The Bluebirds looked in control as a goal from Steve Thomson and a brace from Michael Chopra had the visitors three-up.
However, Ian Holloway's charges never gave up hope and their comeback began when Kevin McNaughton sliced into his own net.
A scrambled goal from Barry Hayles gave Plymouth hope and late on Darren Purse's sensational own goal secured an unlikely point for The Pilgrims.
Norwich missed the chance of bagging their first away Championship win of the campaign after throwing away a 3-1 lead at Southend.
The Shrimpers opened the scoring with Freddy Eastwood lashing home after nine minutes, but it was one-way traffic after that.
Robert Earnshaw's close-range brace put The Canaries in front and Dickson Etuhu's powerful header after the break looked to have clinched the points.
However, Southend failed to read the script and after Steven Hammell pulled one back Mark Gower's fine finish in injury time salvaged a sensational 3-3 draw.
West Brom slipped to their second defeat of the season thanks to Patrick Agyemang's sensational winner for Preston.
With just 12 minutes left at Deepdale the striker lashed the ball home with a superb over-head kick to snatch all three points.
Crystal Palace found themselves behind early on against Southampton and never recovered as they slipped to a 2-0 defeat.
Kenwyne Jones' header had The Saints ahead after just two minutes at Selhurst Park.
The Eagles fought back, but Grzegorz Rasiak's effort shortly after the interval ensured the visitors would return to the South Coast with all three points.
Jay Bothroyd went from hero to villain for Wolves as he missed a penalty in a 1-0 loss to lowly Derby.
The former Blackburn striker stole the points at Leeds on Sunday, but he failed to score from 12 yards that would have put Mick McCarthy's side ahead.
Wolves paid a heavy price for squandering the chance as Steve Howard's first goal for Derby after 34 minutes was enough to give Derby the points.
Hull City's season is up and running after Michael Bridges' first goal for the club lifted The Tigers to a 1-0 away win over Leicester City.
Richard Langley missed a penalty as Luton Town were held by Colchester at Kenilworth Road.
Things looked good early on for the home side when Sam Parkin found the back of the net after 32 minutes.
Jamie Cureton levelled matters before the break with a fine right-footed finish.
Luton should have claimed the points, but Langley saw his penalty strike the crossbar after Kemal Izzet brought him down in the box.
Ipswich Town continued their fine run after Billy Clarke's late goal gave them a 2-1 win over Coventry at Portman Road.
Mark Noble's first senior goal put Ipswich in front but Elliott Ward's left-footed pile-driver levelled matters.
Just when it looked like the points would be shared Clarke popped up five minutes before full time to snatch all three points.
Sheffield Wednesday came from a goal down to claim a 1-1 draw with Stoke City at Hillsborough.
Martin Paterson fired The Potters ahead, but Chris Brunt's penalty after Clint Hill handled in the area secured a point for The Owls.
Gifton Noel-Williams bagged an impressive hat-trick as Burnley fought back from 2-0 down to claim a 4-2 win over Barnsley.
Things looked good for The Tykes after 32 minutes with a brace of goals from Michael McIndoe putting the visitors in firm control of the clash.
Jon Harley pulled one back before half time to give The Clarets hope and after the interval it was the Noel-Williams show.
The former Watford hit-man equalised just before the hour mark and added another two more late on to cap a remarkable comeback.
Click below for match summaries
Burnley 4-2 Barnsley
C.Palace 0-2 Southampton
Ipswich 2-1 Coventry
Leicester 0-1 Hull City
Luton Town 1-1 Colchester
Plymouth 3-3 Cardiff City
Preston NE 1-0 West Brom
QPR 0-2 Birmingham
Sheff Weds 1-1 Stoke City
Southend 3-3 Norwich
Wolves 0-1 Derby