Aaron Hughes, Pat McCourt, Ryan McLaughlin and Niall McGinn have all withdrawn from Northern Ireland's friendly with Finland on Wednesday.
Fulham defender Hughes has been ruled out with an ankle injury, as has Aberdeen's McGinn who was stretchered off during Saturday's SPL draw with Ross County.
McCourt has a groin injury whilst Liverpool youngster McLaughlin misses out on the chance to make his international debut with a hip injury.
Club-less Sammy Clingan, who captained Northern Ireland against Holland in June, has been called up as cover along with Ipswich Town's Josh Carson.
Michael O'Neill has also brought in English-born Will Grigg, who made his senior international debut in the 6-0 defeat by the Dutch.