Portsmouth captain Liam Lawrence is expected to return from an ankle injury for Sunday's local derby against Southampton.
Lawrence has been sidelined for the past six weeks due to a ligament problem and has yet to feature for new Pompey boss Michael Appleton.
However, he resumed full training at the end of last week and, provided he suffers no setbacks, will be back in the squad to face the leaders at Fratton Park.
"He should be fit and available for training all this week," Appleton told The News.
"If that's the case, then he will be fit and available for selection for the Southampton game."
Pompey are also hoping Luke Varney will be fit after the striker suffered a knee injury at Burnley last weekend.