Fiorentina midfielder Riccardo Montolivo has been ruled out for up to six weeks after undergoing ankle surgery.
The 25-year-old Italy international has gone under the knife in Amsterdam to remove a bone fragment from his ankle and will now return to the club to begin his rehabilitation.
Montolivo will miss Italy's friendly clash with Romania next Wednesday and a number of key games for the Viola over the Christmas period.
Meanwhile, goalkeeper Sebastien Frey has undergone surgery on the serious knee problem that will sideline him until the spring.
The 30-year-old French shot-stopper damaged an anterior cruciate ligament in training last week and is set for five months out of action.
Former Celtic goalkeeper Artur Boruc has taken Frey's place in Fiorentina's starting XI, and made his first Serie A appearance in the 1-0 win over Chievo at the weekend.
A statement on the club's official website said: "Fiorentina announces that Sebastien Frey has undergone an operation for anterior cruciate ligament reconstruction performed by Professor Cerulli.
"The player will be discharged from the hospital tomorrow to start rehabilitation in Florence."