Tenth-seeded Milos Raonic came from a set down to beat Andy Murray in the fourth round of the BNP Paribas Open at Indian Wells, extending the British No 1's poor record at the event.
The Wimbledon champion has won only eight matches in total in the Californian desert on his last five visits.
He did look to be on course for the quarter-finals on this occasion as he produced the only break of the first set to take it 6-4.
But his Canadian opponent struck at the end of the second to level the match and then came from a break down in the decider to complete a 4-6 7-5 6-3 victory.
Big-serving Raonic gave notice of his most potent weapon as he thundered down a 140mph ace on the first point of the match.
Two more followed in the opening game, and it was no surprise that it was the Scot who was having more trouble holding serve early on.
Raonic forced a break-point in the sixth game but Murray played a rock solid point to save it and, when his opponent's level dropped in the ninth game, he pounced and broke to love.
He then made it ten points in a row as he served out with no trouble whatsoever to clinch the set.
The second stayed on serve with Murray fending off the only break-point opportunity in the eighth game with an emphatic ace.
But, serving to stay in it at 5-6, the Scot wobbled and fell 0-40 behind. Although he saved the first, Raonic took his second chance as he wrong-footed his rival with a backhand pass to level matters.
It was Murray who claimed the first break of the decider to lead 2-1 but he would play a sloppy game to give it straight back, a double-fault and two consecutive backhand errors ensuring Raonic was quickly on terms.
The Canadian then made the momentum count as he held before notching a second successive break, a heavy forehand down the line proving too hot for Murray to handle.
Murray saved one match point at 3-5, but Raonic took his second with a forehand winner to move through to a quarter-final against Alexandr Dolgopolov.
Dolgopolov followed up his surprise victory over Novak Djokovic by dispatching Italian opponent Fabio Fognini 6-2 6-4, while there was also a fourth round win for Latvia's Ernests Gulbis, who overcame Roberto Bautista-Agut 7-6 (7-0) 4-6 6-2 to book a quarter-final clash with home favourite John Isner.