Wigan coach Shaun Wane and Warrington chief Tony Smith each expect their teams to lay down a marker for the season in a 'Thursday Thriller', on Sky Sports.
The two teams sit eighth and sixth respectively in the Super League table after modest starts to the season ahead of the clash at the Halliwell Jones Stadium.
The Warriors hold bragging rights after coming from behind to win October's Grand Final but that was their only win in the last seven Super League meetings between the sides and Smith is expecting another classic.
"We've had some great games against them in the regular season as well as in some of the finals and we are looking forward to it again," Smith told Boots 'n' All. "It usually brings out the best in both teams.
"They are some of the most intense games of the season and we are hoping that's the case again and we are hoping that we can put on a great show."
Wane added: "The players want to be there [the Grand Final] again - it was a great feeling. I know there are many other clubs in Super League who are going to have a say.
"We all have the same opinion, we all want to win things. It's all about the team that turns up at the end of the year."
This week's match has extra spice following Smith's decision to train with Sydney Roosters, coached by his friend Trent Robinson, ahead of Wigan's 36-14 World Club Challenge defeat in Australia in February.
"The players were very disappointed in what Warrington did but the club chose to do it and that is on their heads," reflected Wane.
"The coach does what he wants. I've forgotten about it now and Thursday is just another game for us - a very, very important game. I'm just bothered about our performance."
But Smith countered: "It will be strange for somebody to be surprised by that, really, because you use the connections that you've got to do whatever you can to prepare for those sorts of games.
"Wigan did the same thing and trained with South Sydney through their connections with Michael Maguire. It was a non-story at the time and I think it's a non-story still."
Boots guest Terry O'Connor said: "The players will be chomping at the bit in the build-up to this game.
"Tony will expect Wigan to come out all guns firing but the Warrington players will be ready for this challenge. I've been there in a Grand Final when you've been beaten.
"It doesn't matter if there has been a change in personnel. The next time that you can play against the opposition that beat you, you want to get out there and whack the opposition."
Watch Warrington take on Wigan from 7.30pm this Thursday on Sky Sports 1 HD.