Harlequins withstood a second-half comeback from Sale Sharks to win 25-23 at the AJ Bell Stadium.
Sale Sharks face Harlequins at the AJ Bell Stadium on Saturday looking to keep their faint top six hopes alive.
Sale's hopes of qualification for next season's European Champions Cup were dealt a blow as they lost at London Irish.
Steve Diamond could not contain his fury at referee Greg Macdonald after his Sale Sharks side lost at London Irish.
London Irish host Sale on Sunday seeking back-to-back Aviva Premiership wins for the first time since February 2014.
Sale recorded a highly-important 23-6 Aviva Premiership win over Gloucester at the AJ Bell Stadium on Sunday.
Mark Cueto will make his 300th appearance for Sale Sharks in Sunday’s Aviva Premiership clash with Gloucester.
Aviva Premiership side Sale Sharks have announced that coach Bryan Redpath has parted company with the club.
Team news for Friday's Aviva Premiership meeting between Bath and Sale Sharks at the Recreation Ground.
Bath full-back Tom Homer kicked four penalties at the Recreation Ground to help them overcome Sale Sharks.
Flanker Magnus Lund has signed a new two-year deal with the Sale Sharks.
Leicester boosted their Premiership play-off chances with a 28-8 win over Sale with tries from Laurence Pearce and Seremaia Bai.
Team news for Saturday's Aviva Premiership meeting between top-four rivals Leicester Tigers and Sale Sharks.
Sale fly-half Danny Cipriani talks to Sky Sports about Stuart Lancaster, his relationship with George Ford and turning down Toulon.
Sale Sharks pulled off a vital 14-10 win over Saracens in the Aviva Premiership on Saturday.
Team news for Saturday's Aviva Premiership clash between Sale Sharks and Saracens at the AJ Bell Stadium.
England's Danny Cipriani has snubbed a big-money move to France to sign a new two-year contract with Sale.
Northampton have confirmed highly-rated Sale lock Michael Paterson will join the club for the 2015/2016 season.
Flanker Dan Braid will play one more season at Sale Sharks before retiring to join the club's coaching staff.
Danny Cipriani has dropped a hint that he will not leave for Toulon this summer because of his desire to play for England.