Munster will aim to keep pace with RaboDirect Pro12 leaders Leinster on Saturday evening when they host Glasgow Warriors at Thomond Park.
The Irish province are unbeaten in all competitions on home this term, while no Scottish side has prevailed on Munster soil since the Warriors' victory in 2008.
Munster captain Peter O'Mahony has been ruled out for the season as he undergoes surgery on an arm injury, meaning fellow back-row James Coughlan will assume leadership duties in his absence.
Duncan Casey and John Ryan come into the front row as two of seven changes from the side which beat Toulouse in the Heineken Cup last weekend, while Donncha O'Callaghan partners Dave Foley in the second row.
JJ Hanrahan comes into the half-back partnership while Keith Earls move to outside centre in the absence of Casey Laulala and Gerhard van den Heever takes Earls' place on the wing.
For Glasgow, Peter Murchie retains the full-back jersey and stands alongside compatriots Sean Maitland and Tommy Seymour in the back line.
Alex Dunbar comes in for Mark Bennett at outside centre, while Duncan Weir replaces Ruaridh Jackson at fly-half and will be partnered in the axis by Chris Cusiter.
Dougie Hall replaces Pat MacArthur at hooker and Jon Welsh comes in for Geoff Cross at tight head, while Tim Swinson and Jonny Gray link up in the engine room and Josh Strauss joins Chris Fusaro in the back row.
Newport Gwent Dragons will look to buck their five-match losing streak when they visit Treviso, who have won just one of their last seven league fixtures.
Antonio Pavanello will again pair Corniel Van Zyl at lock, while the back row will see Robert Barbieri and Paul Derbyshire join Marco Filippucci for Treviso.
Changes to the back line see Mat Berquist at No 10 and Christian Loamanu at inside centre, while Michele Campagnaro and Ludovico Nitoglia feature having recovered from their respective injuries.
Dragons coach Lyn Jones is with Wales international Andrew Coombs, who has been ruled out through injury, leaving Lewis Evans to captain the side in Italy.
The lone change to the Dragons' backs comes at scrum-half, where Wayne Evans replaces Richie Rees, who has been dropped to the bench.
Cory Hill steps in alongside Matthew Screech, in the absence of Andrew Coombs, while skipper Lewis Evans retains his place at flanker in the back row alongside Nic Cudd and British and Irish Lion Taulupe Faletau.
Saturday's final game sees the Scarlets go in search of a fifth successive victory as they host bottom-of-the-table Zebre at the Parc y Scarlets.
Jonathan Davies leads an experienced Scarlets side, with coach Simon Easterby making six changes.
Scrum-half Rhodri Williams is the only switch amongst the backline, replacing injured Gareth Davies, with Aled Davies deputising on the replacements bench.
There is a welcome return to action for fellow Welsh international Aaron Shingler, who makes his first start since January, while Josh Turnbull moves to the right flank with Tongan international Sione Timani packing down at No 8.
George Earle also makes a return from injury and will partner Jake Ball in the second row and a new-look front row sees loose head prop Rob Evans and hooker Emyr Phillips pack down alongside tighthead prop Rhodri Jones.
Andrea Cavinato has made nine changes to his Zebre side that earned a 25-25 draw with Newport Gwent Dragons last time out.
David Odiete gets the nod at full-back while Giovanbattista Venditti replaces Italy winger Leonardo Sarto on the right flank, with Giulio Toniolatti coming in on the opposite wing in place of Dion Berryman.
Tomasso Iannone switches from outside centre to fly-half, with Roberto Quartaroli coming into the midfield alongside Gonzalo Garcia, while Andrea Manici , Dario Chistolini, George Biagi and Filipppo Ferrarini all come into the pack.