Long-serving Edinburgh duo Ben Cairns and Steven Lawrie have been forced to retire from rugby due to long-term knee injuries.
Cairns, 28, made his Scotland debut in the first Test loss to Argentina in June 2008 before playing a crucial part in the victory over the Pumas the following week.
He played six more times for his country, scoring one try, but only featured once in the Six Nations Championship, in 2009, against Wales.
Cairns made 116 club appearances for the Scottish capital club in total, scoring 25 tries.
He said: "I'm going through mixed emotions at the moment. On one hand I'm relieved because I know where I stand but then, when I finally made the call and walked out of the changing room for the last time, it still felt really sudden.
"The frustrating thing is that I haven't been able to decide when I finish so I still feel I have some unfinished business."
Hooker Lawrie, 30, was capped once by Scotland against Samoa in Durban last year after playing both north and south of the border.
The international proved to be Lawrie's last professional match in a career which included 46 appearances, in two stints, for Edinburgh.
He said: "I was always looking forward to the next game and would have liked to have kicked on after getting my first cap for Scotland.
"I'm very proud of the performances I put in for Edinburgh Rugby; for our 2012 run in the Heineken Cup; for being in the first Scotland A squad to beat the England Saxons south of the border; and playing for Scotland was massive.
Edinburgh head coach, Alan Solomons, added: "It's a real shame that both of these players have had their careers cut short in this way.
"However they leave us with incredible experiences and memories earned from representing their local club at an elite level and, of course, realising a dream and playing for their country."