Ulster star Paddy Jackson has been named at fly-half in an Ireland XV to play Fiji at Thomond Park on Saturday.
Coach Declan Kidney has retained just three of the players who started in the 16-12 defeat to South Africa last weekend - captain Jamie Heaslip, prop Mike Ford and scrum-half Conor Murray - for what is a non-cap international in Limerick.
Ireland Under-20s star Jackson was one of the stars of Ulster's sensational run to the Heineken Cup final last season, and he is in prime form this term too.
His Ravenshill team-mates Darren Cave, Craig Gilroy and Luke Marshall will also all start in the back line.
Jackson partners Murray in the half-backs with Marshall and Cave forming their provincial centre partnership outside him.
The back-three comprises the uncapped Gilroy on the left wing with Fergus McFadden on the right and Denis Hurley at full-back.
In the pack David Kilcoyne, who won his first cap last weekend, scrums down with Sean Cronin and Ross and behind them Dan Tuohy and Donncha O'Callaghan make up the second row.
Heaslip keeps his position at No 8 with Ulster's Iain Henderson and Connacht's John Muldoon named at six and seven respectively.
Kidney said: "We know it will be a difficult test and this is a vote of confidence for the players we've picked.
"We know they'll do a job and they've been training really well over the last two and a half weeks. We feel they deserve their go".
Ireland: D Hurley, F McFadden, D Cave, L Marshall, C Gilroy, P Jackson, C Murray, D Kilcoyne, S Cronin, M Ross, D O'Callaghan, D Tuohy, I Henderson, J Muldoon, J Heaslip
Replacements: R Strauss, C Healy, M Bent, D Ryan, C Henry, P Marshall, J Sexton, S Zebo