New Zealand captain Richie McCaw and winger Cory Jane will miss Saturday's Bledisloe Cup Test against Australia through injury.
McCaw was due to play his 121st Test and establish a world record 32nd against Australia, the most recorded by any player against a single team.
But the flanker has been struggling with a tight calf muscle that has forced him to pull out of Steve Hansen's squad.
Jane had been recalled to the All Blacks starting XV for the first time in nine months following a knee ligament injury but he was also forced to withdraw with a slight hamstring strain.
His last game for his country came in the 38-21 defeat to England at Twickenham in December 2012.
Sam Cane replaces McCaw, while Charlie Piutau comes in for Jane to earn only his seventh Test.
Kieran Read takes over the captain's duties.
The All Blacks have already won the Bledisloe Cup after two earlier victories over the Wallabies in the Rugby Championship.
New Zealand: Dagg, Piutau, B Smith, Nonu, Savea, Cruden, A Smith; Woodcock, Mealamu, Faumuina, Thrush, Whitelock, Messam, Cane, Read (capt).
Replacements: Coles, Crockett, Franks, Retallick, Kerr-Barlow, Barrett, Taylor.
You can see New Zealand against Australia in the Bledisloe Cup on Saturday - coverage starts at 7.25am on Sky Sports 4HD