Newcastle, Exeter, London Irish, Cardiff and Connacht recorded bonus-point wins in the Challenge Cup.
Aviva Premiership quartet Wasps, Bath, Northampton and Saracens all face daunting away trips in the Champions Cup.
Sam Hidalgo-Clyne played a starring role as Edinburgh beat Bordeaux-Begles 38-20 to reach the Challenge Cup last eight.
Team news for Sunday's European Rugby Challenge Cup Pool 4 meeting of London Welsh and Lyon at the Kassam Stadium.
Gloucester maintained their perfect record in Pool 5 in the European Challenge Cup with a 31-20 victory over Brive.
London Irish hooker David Paice has been banned for three weeks after he was sent off in their clash with Grenoble.
Exeter produced a powerful second-half display to win at Connacht and reach the European Challenge Cup quarter-finals.
Gloucester progressed to the quarter-finals while London Irish and Newport Gwent Dragons also won in the Challenge Cup.
Cardiff Blues are back on top of Pool One in the European Challenge Cup after an incredible 104-12 victory over Rovigo.
Newport Gwent-Dragons ran in 11 tries as they walloped Bucharest Wolves 69-17 at Rodney Parade.
Newcastle lost their unbeaten record in the European Challenge Cup as Stade Francais won a thrilling Pool 3 tie 31-24.
Wins for Gloucester and Edinburgh in round three of the European Challenge Cup.
Wins for Cardiff Blues, Connacht and Newport Gwent Dragons in round three of the European Challenge Cup.
Newcastle tightened their stranglehold on European Challenge Cup Pool 3 with a 30-23 victory over Stade Francais.
Exeter cemented top spot in European Rugby Challenge Cup Pool 2 with an impressive 36-10 victory at La Rochelle.
Exeter Chiefs ran in five tries during an impressive 33-13 home victory over Connacht in European Challenge Cup Pool 2.
Bordeaux-Begles ran in seven tries to thrash London Welsh 52-20 in Pool 4 of the European Rugby Challenge Cup.
Montpellier coach Mario Ledesma has resigned following the Top 14 club's poor start to the season.
Topsy Ojo impresed as London Irish began their European Rugby Challenge Cup campaign with a 70-14 win over Rovigo.
Cardiff Blues kicked off their European Rugby Challenge Cup campaign with a 37-14 bonus-point victory over Grenoble.
We take a look at the best players according to the statistics in the third round of the 2015 Six Nations.