Leicester Tigers will be without Marcos Ayerza for four to six weeks after the prop suffered a hamstring injury.
Northampton Saints have confirmed the signing of England U20 tight-head prop Paul Hill from Yorkshire Carnegie.
Former England international back Olly Barkley has extended his contract with London Welsh.
Saracens have re-signed England lock George Kruis on a "multi-year contract extension".
Bath have announced the signing of England Sevens international Jeff Williams.
London Welsh have confirmed new contracts for front-rowers Nathan Trevett, Koree Britton, Nathan Morris and Ben Cooper.
Saracens have confirmed promising second rower Maro Itoje has signed a new 'long-term' contract with the club.
Leicester will take on an American side - Rough Riders - in a historic fixture that will be the first elite rugby match played in the USA.
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