Wigan are hot favourites to repeat their Challenge Cup Final success of 1985 when they defeated Hull in what is still widely regarded as the best Wembley show piece in the game's history.
Twenty-eight years ago a side including Aussie superstars Brett Kenny and John 'Chicka' Ferguson pipped a Black and Whites outfit parading another legendary Kangaroo, Peter Sterling, 28-24.
On Saturday much of the focus will be on modern day Wigan kingpin, Sam Tomkins, in what seems certain to be one of his last games before switching to the Australian NRL competition at the end of the season.
Returning to the side in last week's loss to Catalans Dragons, it was the full-back's first appearance for the side since a 22-12 defeat against Warrington back in June.
Despite his lack of game time, he is still 8/13 to cross the white-wash at Wembley and is the shortest price to score a hat-trick than any player of both sides - something which has happened just six times in Challenge Cup Final history.
Despite their recent form, Wigan - who have won just twice in their last seven Super League games - are firm odds-on favourites to lift the famous trophy.
The Cherry and Whites have enjoyed success in this competition of late - they've won it three times since the turn of the century.
In the 90's Wigan were the cup kings, winning eight finals on the bounce from 1988 to 1995 and are appearing in their record-extending 30th cup final appearance.
The Black and Whites of Hull, however, have won only three of their previous fourteen games in the Final, yet they did upset the odds against Leeds in 2005.
Prior to that game, the Airlie Birds were 11/4 to lift the trophy and +10 on the handicap and are a similar price again this weekend.
Gareth Ellis was a loser with Leeds Rhinos that day but on Saturday he will skipper the outsiders and is 18/1 to win the Lance Todd Trophy as man of the match..
Famously, Hull have never won at Wembley yet they do have experience in upsetting the odds in the big games.
As well as being 11/4 in 2005, they were also 7/2 to beat Warrington in the semi-final to reach Saturday's Wembley encounter.
They had a +12 handicap in the last round, yet ran out 16-12 winners at the John Smith's Stadium in Huddersfield - they are 8/1 to win by 1-5 points on Saturday.