England captain Kevin Sinfield will have an operation on his injured thumb on Tuesday and is expected to be ruled out of action for six weeks.
The Leeds star suffered the injury in the first half of England's victory over the Exiles on Friday night.
Sinfield will undergo an operation which is likely to keep him out until the start of August.
Whilst the news is a huge blow for Leeds, he will be fit to lead England's World Cup campaign.
A Leeds statement said: "England captain Kevin Sinfield will have an operation on his thumb on Tuesday after scans revealed the worst case scenario following his injury suffered in the first half of the International Origin game on Friday.
"Sinfield saw specialists on Monday morning to confirm the injury and has been immediately booked in for an operation on Tuesday and is expected to be out of action for up to six weeks."
Sinfield's run of 97 consecutive Super League games therefore comes to an end, leaving England and Leeds team-mate Ryan Hall with the competition's current longest run with 70.
The versatile performer joins a growing list of Rhinos players currently on the sidelines with Carl Ablett (thumb), Ryan Bailey (thumb), Brett Delaney (knee), Stevie Ward (shoulder), Joe Vickery (knee), Liam Hood (ankle), Danny McGuire (leg) and Kallum Watkins (ankle) all currently unavailable.