Harlequins must do with five players for Sunday's engage Super League fixture with Castleford.
The Rugby Football League disciplinary committee came down hard on those involved in various incidents during the stormy 32-26 defeat to Catalans Dragons last Saturday.
Prop Louis McCarthy-Scarsbrook has been handed a three-match ban for his part in a brawl that led to him being sent off.
McCarthy-Scarsbrook, who only recently returned from a three-month lay-off with a broken wrist, was found guilty of punching and also fined £300.
Three of his team-mates, full-back Rikki Sheriffe, centre David Howell and back rower Michael Worrincy, were all given one-match bans and £300 fines after being found guilty of punching during the fracas, which flared up in the final moments of the game in Perpignan.
Tony Clubb is the fifth Quins player to be punished, his one-match ban and £300 fine resulting from a careless high tackle during the first half.
Dragons stand-off Adam Mogg, who was also shown the red card, was given a one-match ban and £300 fine after being found guilty of punching.
It means the Australian will miss the third-placed Catalans' eagerly-awaited clash with champions Leeds at the Gilbert Brutus Stadium on Saturday.
However, Dragons hooker Casey McGuire is free to face the Rhinos after he was fined £300 but avoided a suspension for his part in the brawl.