Last Updated: September 8, 2012 9:06pm
Wenju Liu of China wins gold ahead of bronze medallist Tatyana Mcfadden
Tatyana McFadden, the wheelchair racer abandoned by her parents as a child in Russia, saw her bid for a possible five Paralympic gold medals end with a third-placed finish in the 100 metres at the Olympic Stadium.
In a race which also featured her 16-year-old Albania-born adopted sister Hannah, the 23-year-old could not match the speed of the two Chinese racers, Liu Wenjun and Dong Hongjiao, who took gold and silver.
The sisters have one of the most remarkable and moving stories of the Games.
Tatyana, born with spina bifida in St Petersburg to parents who did not want a disabled child and left for 21 days before being operated on, was sent to an orphanage too poor to afford a wheelchair for her.
She was adopted by Debbie McFadden, who was working as the commissioner of disabilities for the United States health department when she visited the orphanage in 1994 on a business trip.
Severely anaemic and underweight on her arrival in the US, doctors gave he only months to live, but she defied expectations yet again.
Her sister, an above-the-knee amputee who also has a congenital bone problem in her hip, was eighth.
Tatyana McFadden, who has already struck gold in the T54 400m, 800m and 1500m, is also a disability rights campaigner.
"I'm pleased, I'm happy. The 100m is always tough," she said. "In Beijing I came sixth and in London I have three gold medals. I've had a good week.
"It was good to compete with my sister. It was good to have her there. She calmed me down and I calmed her down. It was an awesome experience."
Great Britain's Hazel Robson, Paralympic champion 12 years ago in Sydney, finished seventh in the T36 100m.
The 33-year-old, who has cerebral palsy, clocked a season's best 15.23 seconds.
"I got off to a really good start but my legs felt like jelly towards the end," she said. "It was a really close race though.
"This has been an amazing experience but even with the crowds I can't compare it to Sydney when I won a medal. This is my fourth Paralympics, but if my legs want to I'll keep going."
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