Australia have included Jason Krejza for the series opener against South Africa at the WACA on Wednesday.
The off-spinner is preferred to all-rounder Shane Watson in one of two changes to the XI that beat New Zealand last time out.
Seam bowler Stuart Clark was ruled out earlier in the week due to an elbow injury, opening the door for Tasmanian rookie Peter Siddle to earn his second cap.
Krejza took 12 wickets on his Test debut during the recent tour of India and captain Ricky Ponting believes he can thrive in Perth.
"With the breeze and everything that's on offer at the WACA, we feel that a finger spinner will probably come in handy in this game for us," said Ponting.
Australia and South Africa are ranked number one and two in the world respectively by the International Cricket Council and the hosts are expecting a tough series.
"They are a well rounded side but so are we," noted Ponting, whose team are defending a 16-year unbeaten home record and the number one ranking.
"We have a lot of experience in both the batting and bowling sides of our team.
"Our batsmen are looking forward to the challenge of taking on the South Africans, particularly here at the WACA.
"It's adding up to being a very good series."
South Africa, who have not lost a series in over two years, are set to stick with the same line-up that beat Bangladesh by an innings and 48 runs last month.
A four-man pace attack of Morne Morkel, Makhaya Ntini, Dale Steyn and Monde Zondeki will be supplemented by the captain Graeme Smith's part-time off-spin.
Smith is backing his troops to give a good account of themselves in the three-game rubber.
"Over the last two years the team has developed nicely and moved forward," he said.
"We are in a really good space. The guy's are prepared and excited about it."