The Rainbow Hunter will bid to give Gloucestershire trainer Kim Bailey a second Grand National success 24 years on from Mr Frisk's record-breaking victory in the race.
The horse was unfortunate in last year's renewal when parting company with Aidan Coleman at the Canal Turn on the first circuit when seemingly travelling well.
Even more frustrating for connections is the fact he then went on to jump the remaining 22 fences near-perfectly before chasing the winner Auroras Encore all the way to the line.
With that in mind, coupled with an impressive win in Doncaster's Sky Bet Chase back in January, it looks as if The Rainbow Hunter has every chance of playing a leading role this weekend.
Coleman once again gets the ride and Bailey is happy with the horse ahead of the big day.
He said: "The horse is fine and has been working well.
"As soon as we won the Sky Bet Chase at Doncaster we made the decision then to go straight to Aintree.
"Last year he unseated at the Canal Turn. He didn't make a mistake the whole way round, but unfortunately Aidan was knocked off early on.
"I never feel confident going into the race, but I'm happy with the way he's jumping and he'll stay. I just hope he runs well and comes back in one piece."
Bailey has another runner on National day in the shape of the lightly-raced Un Ace, who takes his chance in the Pertemps Network Mersey Novices' Hurdle on the back of a creditable effort in the Supreme Novices' Hurdle at Cheltenham.
Bailey said: "He ran really well in the Supreme Novices' to finish eighth, and looked to be staying on well at the finish.
"Hopefully the step up in trip can make a big difference and he can run a good race."