Nicky Henderson's Petit Robin heads 35 entries for The Ladbroke at Ascot on Saturday after the six-day entries were released.
The nine-year-old gelding will have to carry top weight of 11-12 in the race after back-to-back victories at Ascot and Sandown in recent weeks.
Petit Robin is one of four entries for Henderson who could also run Cash And Go, Lyvius and First In The Queue, though Darlan won't be running in Berkshire having been taken out of the contest.
Alan King relies on Balder Succes after taking out last year's winner Raya Star while Paul Nicholls also has just the one entry in the form of Ranjaan.
Dermot Weld's Hisaabaat, as short as 10/1 ante-post, won't make the trip over but Ireland are still well represented with Gordon Elliott among those with chances.
He could run both Cause Of Causes and Discoteca.
David Pipe is responsible for six of the entries with Kazlian, Dan Breen, Top Wood, Katkeau, Swing Bowler and Waterunder all possibles for Pond House.
The in-form Emma Lavelle could be represented by Claret Cloak while Olofi and It's A Gimme are other well-fancied horses who could still take their chance.