Monaco sealed a spot in the Champions League thanks to a 1-0 win at Lorient in the final round of Ligue 1 matches.
Liverpool give U21s more game time than Premier League rivals but top flight lags behind Europe.
Nice held off a late Toulouse fightback to win 3-2 in their final game of the Ligue 1 season.
Toulouse will play in Ligue 1 next season despite losing 2-1 at mid-table, 10-man Guingamp.
PSG are on the brink of winning the Ligue 1 title after Caen stunned Lyon 3-0 on Saturday, while Metz were relegated.
Two late goals saw Toulouse come from behind to snatch a 3-2 victory over Lille.