Manchester United take on leaders Chelsea on Super Sunday, while Liverpool welcome Hull City to Anfield on Saturday.
Merse predicts wins for Chelsea, Spurs, QPR and Man City - but sees Arsenal slipping up at Sunderland.
Real Madrid face Barcelona on Saturday in the first El Clasico of the season, with Luis Suarez set to make his debut.
Barcelona's Luis Suarez is adamant his biting days are behind him as he returns from a four-month ban against Real Madrid.
Zenit St Petersburg's Argentina centre-back Ezequiel Garay is reportedly a Manchester United target, plus more from the papers.
QPR must keep starting Bobby Zamora, says Jamie Carragher, and hold fire on recalling Adel Taarabt.