Paderborn moved above Eintracht Frankfurt after coming from behind to beat the Eagles 3-1 at the Paderborn Arena.
Hamburg picked up their first Bundesliga win to pile misery on Borussia Dortmund, while Bayern Munich thrashed Hannover.
Karim Bellarabi grabbed a last-minute equaliser to salvage a 2-2 draw for Bayer Leverkusen at home to Paderborn.
Borussia Monchengladbach moved up to second place in the Bundesliga with a 2-1 win at Paderborn.
Paderborn coach Andre Breitenreiter is to reward his team with a trip to Munich's beer festival on Wednesday.
Bayern Munich kicked Paderborn off the top of the Bundesliga with a thumping 4-0 win over the top-flight newcomers.
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