Montpellier's hopes of muscling in on a European place were all but extinguished after a goalless draw against Rennes.
Top scorer Alexandre Lacazette continued his superb form for Lyon, who took top spot in the table after beating Evian.
Lyon moved back to the top of Ligue 1 with victory at Reims, while there were wins for Monaco and St Etienne.
St Etienne boosted their hopes of a top-three finish in Ligue 1 with a 1-0 victory over Montpellier on Sunday.
Lyon returned to the top of Ligue 1 with a draw against St Etienne, while Lille kept up their hunt for fourth.
Hilton's early header earned Montpellier a narrow 1-0 victory in their Ligue 1 clash with Caen at Stade de la Mosson.