Hoffenheim ended the season with a 2-1 victory over Hertha Berlin.
Liverpool give U21s more game time than Premier League rivals but top flight lags behind Europe.
Bayer Leverkusen all but ended Hoffenheim's hopes of qualifying for Europe next season with a 2-0 win at the BayArena.
Eintracht Frankfurt secured their Bundesliga place with a 3-1 victory over Hoffenheim.
Schalke ended a six-game winless run as Wolfsburg slipped to defeat, plus all the latest from the Bundesliga.
Hoffenheim halted Borussia Dortmund's recent resurgence by taking a 1-1 draw at the Rhein-Neckar Arena.