AZ claim a Europa League place at the expense of Feyenoord, who were consigned to the play-offs for a place in Europe.
NAC Breda face a relegation play-off, while Manchester United-bound Memphis Depay scored for PSV.
PSV came from behind to extend their lead at the top of the Eredivisie standings, while there were wins for Heracles and Utrecht
Champions Ajax delayed PSV's impending Eredivisie title win for another week as they won 2-0 away at Heracles Almelo.
Five-star PSV close in on Dutch title after comprehensive victory at FC Twente, while Heracles grab dramatic late win
Markus Henriksen netted a late winner as AZ strengthened their grip on fourth place with a 2-1 win over Cambuur Leeuwarden.