Mario Gotze and Philipp Lahm hit braces as Bundesliga leaders Bayern Munich romped to a 6-0 victory over Werder Bremen.
Mainz extended their unbeaten run to a club record eight games with a 2-1 win over Augsburg at the Coface Arena.
Borussia Monchengladbach and Mainz both preserved their unbeaten league records this season as they recorded a 1-1 draw.
Augsburg got back to winning ways by beating Hertha Berlin 1-0, to make it an unhappy SGL Arena return for Jos Luhukay.
Son Heung-Min helped get Bayer Leverkusen back to winning ways with the only goal of the game against Augsburg.
Bayern Munich dropped Bundesliga points for only the second time this season, as Borussia Dortmund were defeated.
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