Augsburg only just managed to keep hold of their place inside the top six after a 0-0 draw at home to Cologne.
Cologne left it late to grab a point at home to Bayer Leverkusen in a 1-1 Rhineland derby draw.
Hertha Berlin and Cologne took a point each from their clash, with the goalless draw seemingly satisfying both sides.
Stuttgart boosted their survival hopes with a 3-2 home win over Werder Bremen, while Cologne saw off Hoffenheim by the same scoreline.
Cologne made what could prove to be a decisive step away from the relegation zone with a 3-2 win over Hoffenheim.
Freiburg beat Cologne 1-0 on Saturday to open clear water between themselves and the relegation zone.
Robert Lewandowski was the difference in the German Klassiker, while there were wins for Monchengladbach and Leverkusen
Cologne came from behind to draw 1-1 against Werder Bremen - their seventh home stalemate of the season.
Borussia Dortmund were held to another 0-0 draw to see their hopes of qualifying for Europe next season reduce against Cologne.
Cologne moved clear of the relegation zone with a 4-2 victory over Eintracht Frankfurt.
Cologne coach Peter Stoger is hoping to shock Bundesliga leaders Bayern Munich at the Allianz Arena on Friday.
Cologne and Hannover shared the spoils in an entertaining 1-1 draw on Saturday evening but the result does little for either.
Borussia Monchengladbach left it late to clinch a 1-0 win in the Rhineland derby against Cologne.
Paderborn stalled their slide towards the bottom three as they picked up a point from their trip to Cologne.
Cologne and Stuttgart drew a blank in their Bundesliga contest on Wednesday.
Borussia Dortmund slipped back to the bottom of the Bundesliga despite picking up a point in their goalless draw at Bayer Leverkusen.
Cologne dumped Hamburg right into the thick of a relegation battle with a 2-0 win at the Volksparkstadion.
Wolfsburg reduced Bayern Munich's deficit at the top of the Bundesliga to 11 points after a 2-1 win over Cologne.
Bayern Munich continued their unbeaten start to the Bundesliga season with a 2-0 win over Freiburg on Tuesday night.
Bayern Munich won 4-1 against Cologne on Friday night to move 11 points clear at the top of the Bundesliga.