Fiorentina qualified for the Europa League while Stephan El Shaarawy scored his first goal in seven months for AC Milan.
Liverpool give U21s more game time than Premier League rivals but top flight lags behind Europe.
A last-gasp winner from substitute Marco Sau lifted Cagliari to a 1-0 victory at Cesena.
Napoli and Fiorentina boosted their European qualification hopes with victories over Cesena and Parma in Serie A on Monday.
Napoli kept their hopes of qualifying for the Champions League next season alive with a 3-2 win over Cesena.
Napoli's hopes of Champions League qualification suffered a setback as they drew 2-2 at rock-bottom Parma in Serie A on Sunday.