Reigning champions Sevilla, Inter Milan, PSV and Napoli were amongst the winners in the Europa League group stage.
Schalke crashed to a 4-1 defeat at Borussia Monchengladbach ahead of a Champions League trip to Chelsea.
Freiburg and Borussia Monchengladbach were both left waiting for their first win of the season after a 0-0 draw on Sunday.
Bayern Munich were held to a 1-1 draw by Schalke, while Bayer Leverkusen ran out 4-2 winners against Hertha Berlin.
Tottenham will face Arsenal's UEFA Champions League victims Besiktas in the group stage of the Europa League.
Sky Sports understands Hertha Berlin are leading the chase to sign Lille forward Salomon Kalou.
Live only on