Wolfsburg bounced back from their humbling at the hands of Everton on Thursday by beating 10-man Bayer Leverkusen.
Cologne and Borussia Monchengladbach played out a goalless draw in the Rhine area derby.
Reigning champions Sevilla, Inter Milan, PSV and Napoli were amongst the winners in the Europa League group stage.
Schalke crashed to a 4-1 defeat at Borussia Monchengladbach ahead of a Champions League trip to Chelsea.
Freiburg and Borussia Monchengladbach were both left waiting for their first win of the season after a 0-0 draw on Sunday.
Bayern Munich were held to a 1-1 draw by Schalke, while Bayer Leverkusen ran out 4-2 winners against Hertha Berlin.
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