Carlos Tevez scored twice as Juventus beat Fiorentina 3-2 as the Serie A leaders closed in on a fourth straight title.
AC Milan fans spelled out their deepening frustration over the Serie A giants' malaise before the 3-1 defeat to Genoa.
Udinese delivered a potentially knockout blow to AC Milan's hopes of playing in Europe next season by beating them 2-1.
There was victory for Inter Milan over Roma but AC Milan went down to Udinese in Saturday's Serie A fixtures.
Neither side could find the net in the Milan derby, while Roma missed the chance to go second.
Fallen giants Inter Milan and AC Milan remain mired in mid-table obscurity after Sunday's derby ended goalless.