Dundee chief executive Scot Gardiner is to leave the Scottish Premiership club on Monday.
Gardiner, who previously worked at Rangers and Tottenham, arrived at Dens Park in 2012 to help resolve the club's financial difficulties.
He oversaw a takeover last year by a Texas-based consortium while the Dark Blues returned to the top flight by winning the Scottish Championship in May.
A statement on the Dundee website read: "With the club now back in the Premiership and in good hands, Scot feels that this is the natural time for him to move on and pursue other opportunities within the game."
Gardiner added: "I have greatly enjoyed my time at Dundee FC. It is a fantastic football club and my thanks go to the board, my other colleagues and all the fans for the tremendous support that I have had during my time here.
"I will miss everyone but I leave confident that the club is in good hands and heading in the right direction."
As part of a restructuring at boardroom level, John Nelms will serve as managing director, Ian Crighton will be chief financial officer and Steve Martin will be commercial director.
Gardiner also played a key role in the reformation and merger of the SFL and SPFL leagues last year.