Chelsea's much-anticipated clash against Manchester United became the most notable Premier League casualty to be hit by heavy snow this weekend.
The game, scheduled for Sunday afternoon, was called off due to safety reasons as the treacherous conditions continued to decimate the majority of the weekend's fixtures.
Games at Arsenal, Liverpool, Wigan and Birmingham had already been called off earlier on Saturday, leaving Sunderland versus Bolton and Blackburn versus West Ham as the day's only surviving matches in the top flight.
Sunday's game between Blackpool and Tottenham was also called off, as was the Black Country derby between West Brom and Wolves.
Although Liverpool's pitch is protected by undersoil heating, a club spokesman said the game was called off after police warned of treacherous conditions around the ground, with sub-zero temperatures forecast for later.
Wigan earlier issued a statement confirming their game had been postponed, citing 'freak snow' as the reason, while Birmingham against Newcastle was called off at the request of referee Mike Jones and the local authorities due to safety reasons.
Reigning champions Chelsea had been preparing for the top-of-the-table encounter against the current leaders Manchester United.
However, due to the unprecedented snow and freezing conditions in West London, Police and the local authorities had no other option but to call the fixture off.
With the Blues hoping to go level on points with United, the news will come as a major disappointment to manager Carlo Ancelotti, whose side found some of their old form in the 1-1 draw against Tottenham last weekend.
United, meanwhile were looking to go six points clear off the West London giants with a win on the back of their impressive victory against Arsenal on Monday night.
A date is yet to be set for all rescheduled matches.