Remy Cabella on Monday night helped Ligue 1 title hopefuls Montpellier progress in the French Cup with a 1-0 win at Tours.
Cabella scored the only goal of the game eight minutes after half-time as Rene Girard's men won at the Ligue 2 side.
An away win was always likely, with Montpellier second in Ligue 1 and Tours seventh in the division below.
Both Marseille and Lyon were on Sunday given tough times by lower league opposition before booking their place in the last 16.
Marseille were taken to extra time by second division Le Havre at the Stade Velodrome.
Lyon booked their place in next round with a 2-0 win over Vendee Lucon.