JOLEON LESCOTT v MARCO DEVIC
In the absence of the injured John Terry, Lescott will take over the senior partner role in the centre of defence and will need to be equally commanding. Devic carries the goalscoring burden in the wake of a raft of retirements after Euro 2012 and will no doubt be motivated having had a goal disallowed against England in the tournament this summer.
FRANK LAMPARD v ANATOLIY TYMOSHCHUK
Lampard's second goal against Moldova showed he still has the knack of timing his runs into the penalty area to perfection and his movement could again be key to unlocking Ukraine's defence. The experienced Tymoshchuk's job will be to keep an eye on the Chelsea midfielder and prevent him getting the space to do any damage.
JERMAIN DEFOE v YEVHEN KHACHERIDI
Buoyed by his goal in the opening qualifier, Defoe will be keen to build on that strike and show he is the man to fill in while Wayne Rooney is injured, and possibly stake a claim even when the Manchester United forward returns. Khacheridi will be hoping to fully recover from a reported virus as Ukraine have defensive problems and his recent experience at Euro 2012 will be invaluable.