Uruguay striker Luis Suarez will start against England in their World Cup Group D match in Sao Paulo on Thursday, the country's football association has confirmed.
Suarez, who was recovering from keyhole knee surgery and has not played since May 11, missed Uruguay's 3-1 loss to Costa Rica in their opener and will partner Edinson Cavani in attack, with Diego Forlan dropping to the bench.
Uruguay also bring in Alvaro Pereira, Jose Maria Gimenez, Nicolas Lodeiro and Alvaro Gonzalez, making five changes from the side that lost to Costa Rica.
Sky sources have suggested that the England starting XI will be unchanged from the one that began the game against Italy in Manaus last Saturday.
Uruguay: Muslera, Caceres, Gimenez, Godin, Pereira, Alvaro Gonzalez, Rios, Lodeiro, Rodriguez, Cavani, Suarez.
Subs: Silva, Munoz, Coates, Fucile, Gargano, Perez, Ramirez, Stuani, Forlan, Hernandez.
England: Hart, Johnson, Jagielka, Cahill, Baines, Gerrard, Henderson, Welbeck, Sterling, Rooney, Sturridge.
Subs: Foster, Wilshere, Lampard, Smalling, Jones, Milner, Lambert, Lallana, Barkley, Shaw, Forster.
Referee: Carlos Velasco Carballo (Spain)