The head of the Brazilian Football Federation for more than two decades, Ricardo Teixeira, has left the role and the position as the leader of the 2014 World Cup organising committee.
Health grounds have led to his departure, which was initially a leave of absence but has since been confirmed on a permanent basis.
Teixiera had been in charge of Brazilian football for 23 years, however, he recently came under pressure to resign over allegations of corruption.
A statement read: "I leave the presidency of the CBF (national federation) permanently with the sense of mission accomplished.
"It's not easy to preside passion. Football in our country is associated with two things - talent and disorganisation.
"When we win, talent is praised. When we lose, it's about disorganisation.
"I did what was within my reach, sacrificing my health. I was criticised in the losses and undervalued in the victories."
Former Brazil star Romario, now a congressman, had some harsh words for Teixeira after his resignation.
"Today we can celebrate," Romario posted on his Twitter and Facebook pages. "We exterminated a cancer from Brazilian football. Finally, Ricardo Teixeira resigned."