The Tottenham striker`s father died on Monday evening and he is a doubt for the Group 10 clash and also the match with Albania four days later.
A spokesman for the Football Association of Ireland said: "It`s safe to assume he won`t travel."
The forward issued a statement through his agency, SFX, which read: "My father was a massive influence on my football career, as well as being inspirational in every part of my life.
"He fought a very brave and long fight against cancer, but always remained in good spirits. I considered him more like a brother to me than a father.
"It fills me with pride to remember that the last match he saw me play in was against Everton when I was lucky enough to score a hat-trick.
"I will miss him greatly and I would be very grateful if my family and I could be allowed our privacy to grieve for a wonderful man."
Ireland boss Brian Kerr has already seen Clinton Morrison, Ian Harte, Gary Kelly and Jason McAteer withdraw.
Manchester City defender Richard Dunne, Rotherham's Alan Lee and Stephen McPhail of Leeds have all been drafted in.
