Manchester City midfielder David Silva could be in line for a return to action in Tuesday's Champions League clash at Bayern Munich.
The Spain international has been sidelined for five games due to a calf injury, but he has resumed training and City boss Manuel Pellegrini hopes he will be involved against the European champions.
Silva will not be risked at Southampton on Saturday, and his fitness will be monitored ahead of the team's departure to Munich.
"Maybe on Monday, he will be ready," Pellegrini said. "We'll see the way he works on Saturday and on Sunday, and I will then decide next week."
Pellegrini is also optimistic that captain Vincent Kompany will be able to retain his place for the trip to Southampton.
The Belgium defender played all 90 minutes of Wednesday's 3-2 win over West Brom after being out of action for two months with a thigh injury.
"Vincent is okay. We will see if he can play two matches in less than three days. But he is okay," Pellegrini added.
"It is not an easy decision. But I think he finished the last game without any problem.
"We will wait a few hours more to see that he has made the perfect recovery and I will decide. But I don't think it is a great risk for him to play another game."
Defender Matija Nastasic and striker Stevan Jovetic, who have both also been nursing calf problems, are both ruled out for the Southampton game and are unlikely to return on Tuesday.
Pellegrini will have one eye on next weekend's clash against Premier League leaders Arsenal, who currently have a six-point advantage over City.