PSV Eindhoven's dramatic slump in form continued as they lost to NEC Nijmegen, while Roda JC beat Excelsior and Heerenveen drew with ADO Den Haag.
Fresh from a 3-0 defeat at home to Liverpool in the UEFA Champions League, PSV's run without a win stretched to six games as they lost 2-1 at De Goffert.
Brett Holman (pictured) netted a brace in the space of three first half minutes (22 and 24) to give NEC a two-gaol cushion at the break.
Philip Cocu pulled one back after 61 minutes but PSV could not force an equaliser.
Bottom club ADO came from behind to hold Heerenveen to a 1-1 draw, Santi Kolk (42) cancelling out Alkonso Alves' opener.
Goals from Pa-Modou Kah (48) and Andres Oper (89) helped Roda to a 2-0 victory over struggling Excelsior.
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