PSV Eindhoven stretched their lead at the top of De Eredivisie to six points following a 2-0 win over Heracles Almelo.
The reigning Dutch champions left it late to secure victory on the road, but Peruvian forward Jefferson Farfan set them on their way after 74 minutes.
It was left to Diego Tardelli (92) to seal the win that lays down the gauntlet to nearest challengers Ajax and AZ Alkmaar.
RKC Waalwijk's woes continued as they suffered a 1-0 defeat at NEC Nijmegen.
Edgar Barreto's goal on the hour mark leaves RKC firmly rooted in the relegation zone.
The game between Vitesse Arnhem and Roda JC ended in a 0-0 draw.