PSV Eindhoven moved 12 points clear at the top of De Eredivisie thanks to a 3-1 win over Heerenveen.
The reigning champions were given a helping hand after just 13 minutes when Calvin Jong-A-Pin was dismissed for a professional foul, and Timmy Simons converted the resulting penalty.
Afonso Alves did equalise (21) for his 19th goal of the season, but Arouna Kone's goal (23) and another penalty from Jefferson Farfan (35) secured the points for Ronald Koeman's side.
Twente Enschede moved above Feyenoord into fourth place following a 2-1 win over bottom club RKC Waalwijk.
Kennedy Bakircioglu (13) and Orlando Engelaar (85) struck either side of Ricky van den Bergh's penalty after 26 minutes to earn Twente all three points.
Roda JC were also 2-1 winners, at home to Willem II, as goals from Sekou Cisse (26) and Kemy Agustien (55) sandwiched Kevin Bobson's effort (39).
The game between Heracles Almelo and NEC Nijmegen finished goalless.